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1

Treatment Options for Cystic Fibrosis: Case Study and Panel Discussion

Robert J. Kuhn, Patrick A. Flume

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2002

Language:

english

File:

PDF, 18 KB

english, 2002

2

Aerosolized antibiotic therapy for chronic cystic fibrosis airway infections: continuous or intermittent?

David Lo, Donald R. VanDevanter, Patrick Flume, Alan Smyth

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 129 KB

english, 2011

3

Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

Wainwright, Claire E., Elborn, J. Stuart, Ramsey, Bonnie W., Marigowda, Gautham, Huang, Xiaohong, Cipolli, Marco, Colombo, Carla, Davies, Jane C., De Boeck, Kris, Flume, Patrick A., Konstan, Michael W

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 567 KB

english, 2015

4

Response to Commentary: Regulatory Support Improves Subsequent IRB Approval Rates in Studies Initially Deemed Not Ready for Review—A CTSA Institution’s Experience

Sonne, Susan, Gentilin, Stephanie, Sampson, Royce R., Bell, Leslie, Mauney, Toni, Young, Summer, Bright, Katherine, Flume, Patrick

Journal:

Journal of Empirical Research on Human Research Ethics An International Journal

Year:

2018

Language:

english

File:

PDF, 43 KB

english, 2018

5

Cystic Fibrosis: Advances in Understanding and Treatment

Flume, Patrick A., Goss, Christopher H., VanDevanter, Donald

Journal:

Seminars in Respiratory and Critical Care Medicine

Year:

2019

File:

PDF, 59 KB

2019

6

Finding the relevance of antimicrobial stewardship for cystic fibrosis

Cogen, Jonathan D., Kahl, Barbara C., Maples, Holly, McColley, Susanna A, Roberts, Jason A., Winthrop, Kevin L., Morris, Andrew M., Holmes, Alison, Flume, Patrick A, VanDevanter, Donald R., Waters, Va

Journal:

Journal of Cystic Fibrosis

Year:

2020

File:

PDF, 1.15 MB

2020

7

Transition programs in cystic fibrosis centers: Perceptions of patients

Deborah L. Anderson, Patrick A. Flume, Kristina K. Hardy, Sue Gray

Journal:

Pediatric Pulmonology

Year:

2002

Language:

english

File:

PDF, 57 KB

english, 2002

8

Transition programs in cystic fibrosis centers: Perceptions of team members

Patrick A. Flume, Lloyd A. Taylor, Deborah L. Anderson, Sue Gray, David Turner

Journal:

Pediatric Pulmonology

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

9

Transition programs in cystic fibrosis centers: Perceptions of pediatric and adult program directors

Patrick A. Flume, Deborah L. Anderson, Kristina K. Hardy, Sue Gray

Journal:

Pediatric Pulmonology

Year:

2001

Language:

english

File:

PDF, 374 KB

english, 2001

10

Superior vena cava syndrome related to indwelling intravenous catheters in patients with cystic fibrosis

Susan Garwood, Patrick A. Flume, James Ravenel

Journal:

Pediatric Pulmonology

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

11

A role for aerosolized antibiotics

Patrick A. Flume

Journal:

Pediatric Pulmonology

Year:

2008

Language:

english

File:

PDF, 122 KB

english, 2008

12

Hepatopulmonary syndrome occurring after orthotopic liver transplantation

Christopher E. Avendano, Patrick A. Flume, Prabhakar Baliga, David N. Lewin, Charlie Strange, Adrian Reuben

Journal:

Liver Transplantation

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

13

An unusual presentation of cystic fibrosis in an adult

Shoban Davé, Shanon Honney, John Raymond, Patrick A. Flume

Journal:

American Journal of Kidney Diseases

Year:

2005

Language:

english

File:

PDF, 78 KB

english, 2005

14

A Pilot Study of the Efficacy of Constant-Infusion Ceftazidime in the Treatment of Endobronchial Infections in Adults with Cystic Fibrosis

Dr. John A. Bosso, Dr. Charles R. Bonapace, Dr. Patrick A. Flume, Dr. Roger L. White

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1999

Language:

english

File:

PDF, 47 KB

english, 1999

15

The Rationale for Aerosolized Antibiotics

Dr. Patrick Flume, Dr. Michael E. Klepser

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

2002

Language:

english

File:

PDF, 154 KB

english, 2002

16

The Fowler breathholding study revisited: continuous rating of respiratory sensation

Patrick A. Flume, Frederic L. Eldridge, Lloyd J. Edwards, Lynn M. Houser

Journal:

Respiration Physiology

Year:

1994

Language:

english

File:

PDF, 785 KB

english, 1994

17

Relief of distress of breathholding: separate effects of expiration and inspiration

Patrick A. Flume, Frederic L. Eldridge, Lloyd J. Edwards, Lynn M. Houser

Journal:

Respiration Physiology

Year:

1995

Language:

english

File:

PDF, 497 KB

english, 1995

18

Relief of the ‘air hunger’ of breathholding. A role for pulmonary stretch receptors

Patrick A. Flume, Frederic L. Eldridge, Lloyd J. Edwards, Lalaine E. Mattison

Journal:

Respiration Physiology

Year:

1996

Language:

english

File:

PDF, 900 KB

english, 1996

19

Cost-effective airway cultures in the cystic fibrosis patient

Mark D. Ghegan, Sarah K. Wise, David R. White, Patrick A. Flume, C. Michael Bowman, Isabel Virella-Lowell, Rodney J. Schlosser

Journal:

American Journal of Otolaryngology

Year:

2009

Language:

english

File:

PDF, 101 KB

english, 2009

20

Pulmonary complications after esophagectomy

Christopher E Avendano, Patrick A Flume, Gerard A Silvestri, Lydia B King, Carolyn E Reed

Journal:

The Annals of Thoracic Surgery

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

21

Introduction

Patrick A. Flume

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 91 KB

english, 2011

22

Applying clinical outcome variables to appropriate aerosolized antibiotics for the treatment of patients with cystic fibrosis

Donald R. VanDevanter, Manfred Ballmann, Patrick A. Flume

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 136 KB

english, 2011

23

Impact of lung transplantation on site of death in cystic fibrosis

Dee Ford, Patrick A. Flume

Journal:

Journal of Cystic Fibrosis

Year:

2007

Language:

english

File:

PDF, 201 KB

english, 2007

24

Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis

Patrick A. Flume, Jody Ciolino, Susan Gray, Mary K. Lester

Journal:

Journal of Cystic Fibrosis

Year:

2009

Language:

english

File:

PDF, 217 KB

english, 2009

25

Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: The EAGER trial

Michael W. Konstan, Patrick A. Flume, Matthias Kappler, Raphaël Chiron, Mark Higgins, Florian Brockhaus, Jie Zhang, Gerhild Angyalosi, Ellie He, David E. Geller

Journal:

Journal of Cystic Fibrosis

Year:

2011

Language:

english

File:

PDF, 290 KB

english, 2011

26

Treatment of lung infection in patients with cystic fibrosis: Current and future strategies

Gerd Döring, Patrick Flume, Harry Heijerman, J. Stuart Elborn

Journal:

Journal of Cystic Fibrosis

Year:

2012

Language:

english

File:

PDF, 498 KB

english, 2012

27

State of progress in treating cystic fibrosis respiratory disease

Patrick A Flume, Donald R Van Devanter

Journal:

Year:

2012

Language:

english

File:

PDF, 355 KB

english, 2012

28

Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

Flume, Patrick A.

Journal:

Year:

2012

Language:

english

File:

PDF, 834 KB

english, 2012

29

Cystic Fibrosis Pulmonary Guidelines

Flume, Patrick A., Mogayzel, Peter J., Robinson, Karen A., Goss, Christopher H., Rosenblatt, Randall L., Kuhn, Robert J., Marshall, Bruce C.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 101 KB

english, 2009

30

Cystic Fibrosis Pulmonary Guidelines

Flume, Patrick A., Mogayzel, Peter J., Robinson, Karen A., Rosenblatt, Randall L., Quittell, Lynne, Marshall, Bruce C.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 122 KB

english, 2010

31

Timing of inhaled tobramycin affects assessment of intravenous tobramycin pharmacokinetic monitoring

Stenbit, Antine E., Bullington, Wendy M., Heh, Julie L., Flume, Patrick A.

Journal:

Journal of Cystic Fibrosis

Year:

2013

Language:

english

File:

PDF, 203 KB

english, 2013

32

Detection of an Apparent Homozygous 3120G>A Cystic Fibrosis Mutation on a Routine Carrier Screen

Heaney, Denise LaMarche, Flume, Patrick, Hamilton, Lauren, Lyon, Elaine, Wolff, Daynna J

Journal:

The Journal of Molecular Diagnostics

Year:

2006

Language:

english

File:

PDF, 367 KB

english, 2006

33

Pooled analysis of two large randomised phase III inhaled mannitol studies in cystic fibrosis

Bilton, Diana, Bellon, Gabriel, Charlton, Brett, Cooper, Peter, De Boeck, Kris, Flume, Patrick A., Fox, Howard G., Gallagher, Charles G., Geller, David E., Haarman, Eric G., Hebestreit, Helge U., Kolb

Journal:

Journal of Cystic Fibrosis

Year:

2013

Language:

english

File:

PDF, 682 KB

english, 2013

34

Cystic Fibrosis Pulmonary Guidelines

Flume, Patrick A., O'Sullivan, Brian P., Robinson, Karen A., Goss, Christopher H., Mogayzel, Peter J., Willey-Courand, Donna Beth, Bujan, Janet, Finder, Jonathan, Lester, Mary, Quittell, Lynne, Rosenb

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 178 KB

english, 2007

35

European Cystic Fibrosis Society Standards of Care: Best Practice guidelines

Smyth, Alan R., Bell, Scott C., Bojcin, Snezana, Bryon, Mandy, Duff, Alistair, Flume, Patrick, Kashirskaya, Nataliya, Munck, Anne, Ratjen, Felix, Schwarzenberg, Sarah Jane, Sermet-Gaudelus, Isabelle,

Journal:

Journal of Cystic Fibrosis

Year:

2014

Language:

english

File:

PDF, 302 KB

english, 2014

36

Lung Clearance Index. A Potential Quantitative Tool to Assess Treatment Response in Bronchiectasis?

Hill, Adam T., Flume, Patrick A.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

37

Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): two randomised double-blind, placebo-controlled phase 3 trials

Barker, Alan F, O'Donnell, Anne E, Flume, Patrick, Thompson, Philip J, Ruzi, Jonathan D, de Gracia, Javier, Boersma, Wim G, De Soyza, Anthony, Shao, Lixin, Zhang, Jenny, Haas, Laura, Lewis, Sandra A,

Journal:

The Lancet Respiratory Medicine

Year:

2014

Language:

english

File:

PDF, 419 KB

english, 2014

38

Book Review

Journal:

Journal of Cystic Fibrosis

Year:

2015

Language:

english

File:

PDF, 66 KB

english, 2015

39

Clinical applications of pulmonary delivery of antibiotics

Flume, Patrick A., VanDevanter, Donald R.

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 511 KB

english, 2015

40

A Preliminary Quality of Life Questionnaire-Bronchiectasis

Quittner, Alexandra L., Marciel, Kristen K., Salathe, Matthias A., O’Donnell, Anne E., Gotfried, Mark H., Ilowite, Jonathan S., Metersky, Mark L., Flume, Patrick A., Lewis, Sandra A., McKevitt, Matthe

Journal:

Year:

2014

Language:

english

File:

PDF, 618 KB

english, 2014

41

Efficacy and safety of ivacaftor in patients with cystic fibrosis who have an Arg117His-CFTR mutation: a double-blind, randomised controlled trial

Moss, Richard B, Flume, Patrick A, Elborn, J Stuart, Cooke, Jon, Rowe, Steven M, McColley, Susanna A, Rubenstein, Ronald C, Higgins, Mark

Journal:

The Lancet Respiratory Medicine

Year:

2015

Language:

english

File:

PDF, 594 KB

english, 2015

42

The Clinical Approach to Lung Disease in Patients with Cystic Fibrosis

O'Sullivan, Brian, Flume, Patrick

Journal:

Seminars in Respiratory and Critical Care Medicine

Year:

2009

Language:

english

File:

PDF, 170 KB

english, 2009

43

Transmissibility of Pseudomonas cepacia Infection in Clinic Patients and Lung-Transplant Recipients with Cystic Fibrosis

Steinbach, Suzanne, Sun, Li, Jiang, Ru-Zhang, Flume, Patrick, Gilligan, Peter, Egan, Thomas M., Goldstein, Richard

Journal:

Boston Medical and Surgical Journal

Year:

1994

Language:

english

File:

PDF, 6.98 MB

english, 1994

44

Intravenous antibiotics for pulmonary exacerbations in people with cystic fibrosis

Hurley, Matthew N., Prayle, Andrew P., Flume, Patrick

Journal:

Paediatric Respiratory Reviews

Year:

2015

Language:

english

File:

PDF, 556 KB

english, 2015

45

Update in Cystic Fibrosis 2010

Mogayzel, Peter J., Flume, Patrick A.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

46

Levofloxacin Inhalation Solution (MP-376) in Patients with Cystic Fibrosis with Pseudomonas aeruginosa

Geller, David E., Flume, Patrick A., Staab, Doris, Fischer, Rainald, Loutit, Jeffery S., Conrad, Douglas J.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2011

Language:

english

File:

PDF, 388 KB

english, 2011

47

Cystic Fibrosis

Flume, Patrick A.

Journal:

Year:

1998

Language:

english

File:

PDF, 1.81 MB

english, 1998

48

Pneumothorax in Cystic Fibrosis

Flume, Patrick A, Strange, Charlie, Ye, Xiaobu, Ebeling, Myla, Hulsey, Thomas, Clark, Leslie L

Journal:

Year:

2005

Language:

english

File:

PDF, 216 KB

english, 2005

49

A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients

Flume, Patrick A., VanDevanter, Donald R., Morgan, Elizabeth E., Dudley, Michael N., Loutit, Jeffery S., Bell, Scott C., Kerem, Eitan, Fischer, Rainald, Smyth, Alan R., Aaron, Shawn D., Conrad, Dougla

Journal:

Journal of Cystic Fibrosis

Year:

2016

Language:

english

File:

PDF, 477 KB

english, 2016

50

Safety and efficacy of prolonged levofloxacin inhalation solution (APT-1026) treatment for cystic fibrosis and chronic Pseudomonas aeruginosa airway infection

Elborn, J. Stuart, Flume, Patrick A., Cohen, Fredric, Loutit, Jeffery, VanDevanter, Donald R.

Journal:

Journal of Cystic Fibrosis

Year:

2016

Language:

english

File:

PDF, 405 KB

english, 2016